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    TAKARA Cellartis®iPS移植后人細胞檢測抗體

    簡要描述:熱烈祝賀華雅生物成為TAKARA Cellartis®干細胞研究產品的全國代理商
    TAKARA Cellartis®干細胞研究產品研發團隊上百人,憑借20多年干細胞以及相關培養基研發經驗,研發并上市干細胞研究相關的多種產品,包括干細胞培養基,IPS干細胞系,干細胞分化細胞以及培養基,干細胞檢測抗體等;產品品種豐富,*,具有配方和*的產品特質.

    • 產品型號:
    • 廠商性質:代理商
    • 更新時間:2025-02-13
    • 訪  問  量:1204
    詳細介紹
    監控人類細胞移植用途的抗體
    (Antibodies for Detecting Human Cells Transplanted into Mice and Rats)
    STEM101、STEM121、STEM123是三種小鼠來源的單克隆抗體,用于人類細胞向小鼠和大鼠移植實驗中,監控細胞移植、轉移、分化。
     
    ■ 產品特點
    · STEM101 reacts specifically with the nuclear human Ku80 protein; the antibody does not cross-react with mouse 
       or rat Ku80 in brain tissue or cell extracts 
    · STEM121 reacts with a human cytoplasmic protein expressed in brain, liver, pancreas, and CNS cells 
       the antibody does not cross-react with brain tissue or cell extracts from mouse, rat, or cynomologous monkey
    · STEM123 reacts specifically with human GFAP, a marker of astroglial cells; the antibody does not cross-react 
       with brain tissue or cell extracts from mouse or rat
     
    ■ 產品應用
    · Localization, quantification, and/or characterization of engrafted cells of human origin by immunohistochemistry 
       and immunofluorescence
     
    Code No.ProductSize
    Y40400STEM101®50 μg
    Y40410STEM121®50 μg
    Y40420STEM123®50 μg
     

    ■ 產品詳情

     
    STEM101 detects nuclei of transplanted human neural stem cells in the olfactory bulb of a mouse brain.
     
    STEM121 detects migration and differentiation of transplanted human neural stem cells in the hippocampus of a mouse brain.
     
    STEM123 detects human GFAP+ astrocytes differentiated from human neural stem cells after transplantation into a mouse brain.
     
    參考文獻:
    1. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal 
        cord-injured mice. PNAS 102: 14069-14074.
    2. Guzman R, et al. (2007) Long-term monitoring of transplanted human neural stem cells in developmental and 
        pathological contexts with MRI. PNAS 104: 10211-10216.
    3. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse 
        Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319.
    4. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early 
        Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5: e12272.
    5. Kelly S, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat 

     


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