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    GMP Recombinant Human Interleukin-4 (rh IL-4), USP grade

    簡要描述:GMP Recombinant Human Interleukin-4 (rh IL-4), USP grade USP級人重組白介素4
    品牌: CellGro®
    廠家: CellGen
    貨號: 352096
    貨期:期貨2-5周

    • 產品型號:1003-050
    • 廠商性質:代理商
    • 更新時間:2025-02-12
    • 訪  問  量:1692
    詳細介紹

    咨詢:  (重慶) (貴陽)

    GMP Recombinant Human Interleukin-4 (rh IL-4), USP grade USP級人重組白介素4產品信息:

    Data Sheet: CellGro®/ CellGenix™

    GMP Recombinant Human

    Interleukin-4 (rh IL-4), USP grade

    Order No.: 1003-050

    Source

    A DNA sequence encoding the mature IL-4 protein (Yakota, T. et al., 1986,

    PNAS 83:5894) was expressed in E. coli

    Molecular mass

    The methionyl form of the E. coli expressed mature human IL-4 contains 130 amino acid residues and has a molecular mass of 14 kDa

    Identity

    Confirmed by DNA-sequencing of the expression plasmid in end of production (EOP)-cells, Western Blot, and N-terminal sequencing of the final product

    Purity

    ≥97%, as determined by SDS-PAGE (under reducing and non-reducing

    conditions) and visualized by Silver staining

    Endotoxin level

    < 50 EU/mg, as determined by LAL gel clot test according to Ph.Eur.

    Residual host-cell DNA

    ≤1 ng/mg, as determined with the Threshold®system

    Activity

    0.5x107 – 2x107

    USP units per mg1

    Measured in a cell proliferation assay using a human factor-dependent cell line, TF-1 (Kitamura, T. et al., 1989, J. Cell Physiol. 140:323-334) USP units are equivalent to international units (IU)

    Sterility

    Sterility test according to Ph.Eur. of the vialed product (direct inoculation)

    Formulation

    Lyophilized from a 250 μg/ml, 0.2μm sterile-filtered solution in PBS without any carrier materials and preservatives

    Amount per vial

    50 ± 7.5 μg, as determined by spectrophotometrical measurement at 280 nm

    using PBS as reference (A280= 0.63 for a concentration of 1 mg/ml IL-4 in PBS)

    Transport

    Ambient temperature

    Storage at

    -20°C or below. Avoid repeated freeze-thaw cycles

    Shelf life

    Minimum 6 months from date of shipping

    Intended use

     For clinical ex vivo use. Not intended for human in vivo application

    Quality statement

    This product is manufactured, tested and released in compliance with the relevant GMP-guidelines. No animal- or human-derived materials were used during manufacturing. This product complies with USP chapter  “growth factors and cytokines used in cell therapy manufacturing”. USP chapter  “ancillary materials for cell, gene, and tissue-engineered products” has been considered in the design of this product.

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    更多詳情請來電:       :

    重慶市華雅干細胞技術有限公司

     

     

     


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