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    Anti-Cdk9 antibody 抗細胞周期依賴性激酶抗體

    簡要描述:Anti-Cdk9 antibody 抗細胞周期依賴性激酶抗體
    貨號:ab124261
    廠家:Abcam公司
    規格:40ul/100ul
    保存溫度:-20℃ 和 2~8℃
    貨期:現貨2~5天,期貨2-3周

    • 產品型號:ab124261
    • 廠商性質:代理商
    • 更新時間:2025-02-12
    • 訪  問  量:1042
    詳細介紹

    Anti-Cdk9 antibody 抗細胞周期依賴性激酶抗體

    • Product nameAnti-Cdk9 antibodySee all Cdk9 primary antibodies ...
    • Description

      Rabbit polyclonal to Cdk9

    • Tested applicationsIP more details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan

    • Immunogen

      Synthetic peptide, corresponding to to a region within amino acids 1-50 of Human Cdk9 (NP_001252.1).

    • Positive control
      • HeLa whole cell lysate

    Properties

    • FormLiquid
    • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    • Storage bufferPreservative: 0.09% Sodium azide
      Constituent: 99% Tris citrate/phosphate
      Note: pH 7 to 8
    • Concentration 100 µg at 1 mg/ml

    • PurityImmunogen affinity purified
    • Purification notesab124261 was affinity purified using an epitope specific to Cdk9 immobilized on solid support .
    • Clonality Polyclonal
    • IsotypeIgG
    • Applications

      Our Abpromise guarantee covers the use of ab124261 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      ApplicationNotes
      IPIP: Use at 2-10 µg/mg of lysate.
    • Application notesIs unsuitable for or WB.
    • Target

    • FunctionMember of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro.
    • Tissue specificityUbiquitous.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
      Contains 1 protein kinase domain.
    • Cellular localizationNucleus.
    • Alternative names

    • C-2K antibody
    • CDC2 related kinase antibody
    • CDC2L4 antibody
    • Anti-Cdk9 antibody images

    • Immunoprecipitation - Anti-Cdk9 antibody (ab124261)

      Immunoprecipitation - Anti-Cdk9 antibody (ab124261)

      Anti-Cdk9 antibody which recognizes a downstream epitope of Cdk9 was used at 1 µg/ml detecting Cdk9 in HeLa whole cell lysate by WB following IP.

      Lane 1: IP with ab124261 at 6 µg/mg of lysate.
      Lane 2: IP with an antibody which recognizes an downstream epitope of Cdk9.
      Lane 3: Control IgG.

      In each case, 1 mg of lysate was used for IP and 20% of the IP was loaded.

      Detection: Chemiluminescence with an exposure time of 10 seconds.

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    Abcamab12029Mouse monoclonal [HAP46.5] to HMGB1100ul4274HMGB1hystemcell一抗

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    Abcamab12034Mouse monoclonal [REMB1] to LEF150ug3885LEF1hystemcell一抗

    Abcamab12035Mouse monoclonal [REMB6] to LEF150ug3996LEF1hystemcell一抗

    Abcamab12036Sheep polyclonal to LEF150ug3996LEF1hystemcell一抗

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    Abcamab1133Rabbit polyclonal to GABARAP100ul3996GABARAP抗體一抗

    更多詳情,請:     

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